Synthesis of 5-amino-1-aryl-4-cyanoimidazoles from formamidines under solvent-free condition
نویسندگان
چکیده مقاله:
The aryl-(Z)-N-[2-amino-1,2-dicyanovinyl]formamidine 2 cyclize in solvent-free conditions and in the presence of a base to give a 5-amino-1-aryl-4-cyanoimidazoles 3. Silica sulfuric acid as an efficient and reusable heterogeneous catalyst has been used for the preparation of amidines 2 from formimidate 1 through reaction with aromatic amines at room temperature and in good to excellent yields. All these derivatives were fully characterized by spectroscopic data.
منابع مشابه
synthesis of 5-amino-1-aryl-4-cyanoimidazoles from formamidines under solvent-free condition
the aryl-(z)-n-[2-amino-1,2-dicyanovinyl]formamidine 2 cyclize in solvent-free conditions and in the presence of a base to give a 5-amino-1-aryl-4-cyanoimidazoles 3. silica sulfuric acid as an efficient and reusable heterogeneous catalyst has been used for the preparation of amidines 2 from formimidate 1 through reaction with aromatic amines at room temperature and in good to excellent yields. ...
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عنوان ژورنال
دوره 3 شماره 1
صفحات 9- 13
تاریخ انتشار 2013-03-01
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